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Article

Proteomic biomarkers of emphysema-predominant and non-emphysema-predominant chronic obstructive pulmonary disease

12 Jun 2025

Abstract excerpt

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a complex and heterogeneous disease. Emphysema-predominant and non-emphysema predominant COPD are two major disease subtypes capturing important aspects of COPD heterogeneity. Molecular differences between these COPD subtypes are unknown. METHODS: We assessed plasma proteomic associations (using SomaScan) with emphysema-predominant vs. non-emphysema...

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PMID: 40505416
DOI: 10.1016/j.ebiom.2025.105800

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