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Article

Primer-walking sequencing identifies predominantly noncoding TP53 variants in canine cancers.

Journal of veterinary science - 1 Jul 2026

Mathiyalagan Ramya, Lee Chanjoong, Jo Yongsuk, Lee Jaebeom, Song Joong-Hyun

Abstract excerpt

IMPORTANCE: Tumor protein p53 (TP53) alterations are frequently reported in canine cancers but remain incompletely characterized due to differences in reference genomes and sequencing cost. OBJECTIVE: To evaluate a cost-efficient primer-walking approach for TP53 variant screening in dogs with spontaneous tumors. METHODS: Tumor tissue (n = 10) or blood (n = 16) was collected from 26 dogs with suspected neoplasia....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42551979
DOI: 10.4142/jvs.25325
PMCID: PMC13454805

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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