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Cytokine Gene Variants Are Associated With Aerobic Fitness‐Related, Hematological, and Metabolic Traits in Healthy Adults

31 Jul 2026

Abstract excerpt

ABSTRACT Genetic variation in cytokine genes may influence cytokine‐related signaling, metabolism, and exercise‐related phenotypes, yet large‐scale population data remain scarce. This study examined whether five polymorphisms in interleukin‐6 (IL6; rs1800795; rs1800796; rs1800797), interleukin‐15 (IL15; rs1589241), and tumor necrosis factor‐alpha (TNF‐α; rs1800629) associate with physiological, biochemical, and...

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PMID: 42544145
DOI: 10.1002/cph4.70234

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