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Article

IL6R haplotype rs4845625T/rs4537545C is a risk factor for simultaneously high CRP, LDL and ApoB levels.

Genes and immunity - 1 Sept 2017

Arguinano A A, Naderi E, Ndiaye N C, Stathopoulou M, Dadé S, Alizadeh B, Visvikis-Siest S

Abstract excerpt

Interleukin 6 receptor (IL-6R), mediating IL-6's biological functions, plays an important role in different diseases such as diabetes, obesity and cardio-vascular diseases. In this study, we investigated the effects of two single nucleotide polymorphisms (SNPs), within the IL-6R loci, previously associated with C-reactive protein (CRP) and coronary heart diseases risk, and with controversial effects on lipids...

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Share to Apolipoproteins B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin-6

Source

Identifiers

PMID: 28769070
DOI: 10.1038/gene.2017.16

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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