Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of inflammatory proteins in mediating the effect of cathepsins on cholelithiasis: A mendelian randomization study.

Science progress - 1 Jan 2026

Yuan Tong, Wang Ting

Abstract excerpt

ObjectivePrevious studies have suggested potential associations between cathepsins and cholelithiasis. This study aimed to investigate the potential causal relationships among cathepsins, inflammatory proteins, and cholelithiasis using Mendelian randomization (MR), and to explore whether inflammatory proteins mediate the association between cathepsins and cholelithiasis.MethodsWe conducted a two-sample MR study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cathepsin B
Share to Cathepsins
Share to Cholelithiasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Inflammation

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 42541384
DOI: 10.1177/00368504261475473

Genes

FGF19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of inflammatory proteins in mediating the effect of cathepsins on cholelithiasis: A mendelian randomization study.PMID 42541384Read ↗

Cysteine cathepsins and autoimmune diseases: A bidirectional Mendelian randomization.Semantic proximity Read ↗

A two-sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy.Semantic proximity Read ↗

Insights into modifiable risk factors of cholelithiasis: A Mendelian randomization study.Semantic proximity Read ↗

Relationship between cathepsins and cardiovascular diseases: a Mendelian randomized studySemantic proximity Read ↗

Genetic insights into the role of cathepsins in cardiovascular diseases: a Mendelian randomization study.Semantic proximity Read ↗

The causal relationship between cathepsins and hepatocellular carcinoma risk: A Mendelian randomization studySemantic proximity Read ↗

Causal effects of cholelithiasis on acute pancreatitis and hepatic bile duct cancer: a multi-cohort Mendelian randomization studySemantic proximity Read ↗

Cathepsins and drug target genes in chronic gastritis: Deciphering potential therapeutic mechanisms via Mendelian randomization analysisSemantic proximity Read ↗

Immune cell traits and causal relationships with cholecystitis: a mendelian randomization analysis.Semantic proximity Read ↗

Identification of blood metabolites linked to the risk of cholelithiasis: a comprehensive Mendelian randomization study.Semantic proximity Read ↗

A Mendelian randomization study: Association of Cathepsin with Osteoarticular Muscle DiseasesSemantic proximity Read ↗

Cathepsins and age-related macular degeneration: A Mendelian randomization study unveiling causal relationships.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.