Article
Insights into modifiable risk factors of cholelithiasis: A Mendelian randomization study.
Hepatology (Baltimore, Md.) - 1 Apr 2022
Chen Lanlan, Yang Hongqun, Li Haitao, He Chang, Yang Liu, Lv Guoyue
Abstract excerpt
BACKGROUND AND AIMS: The risk factors of cholelithiasis have not been clearly identified, especially for total cholesterol. Here, we try to identify these causal risk factors. APPROACH AND RESULTS: We obtained genetic variants associated with the exposures at the genome-wide significance (p < 5 × 10-8 ) level from corresponding genome-wide association studies. Summary-level statistical data for cholelithiasis...
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