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Article

Genetic insights into the role of cathepsins in cardiovascular diseases: a Mendelian randomization study.

ESC heart failure - 1 Oct 2024

Zeng Ruiqi, Zhou Zhiyi, Liao Wanzhe, Guo Beian

Abstract excerpt

AIMS: This study aimed to explore the causal relationships between cathepsins and cardiovascular diseases (CVDs) by Mendelian randomization (MR) analysis. METHODS AND RESULTS: Single nucleotide polymorphisms (SNPs) associated with nine cathepsin types (cathepsins B, E, F, G, H, O, S, L2, and Z) were obtained from the INTERVAL study (3301 individuals). CVDs data were acquired from the UK Biobank (coronary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38714485
DOI: 10.1002/ehf2.14826
PMCID: PMC11424349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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