Evidence for genetic association between Hashimoto's thyroiditis and Sjögren's syndrome: a two-sample bidirectional mendelian randomization study.

doi:10.1007/s10067-026-08341-2

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Article

Evidence for genetic association between Hashimoto's thyroiditis and Sjögren's syndrome: a two-sample bidirectional mendelian randomization study.

Clinical rheumatology - 1 Sept 2026

Wang Haikun, Ma Zichuang, Wu Na

Abstract excerpt

BACKGROUND: Hashimoto's thyroiditis (HT) and Sjögren's syndrome (SS) frequently co-occur clinically, implying a potential association between the two diseases. However, their genetic association remains unclarified. To investigate whether there is a genetic link between HT and SS, we performed a two-sample bidirectional Mendelian randomization (MR) analysis. METHODS: Data for HT were obtained from the IEU Open...

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PMID: 42536326
DOI: 10.1007/s10067-026-08341-2

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