Identifying the Genetic Association Between Sjogren's Syndrome and Autoimmune Thyroid Disease: A Bidirectional Two-Sample Mendelian Randomization Study.

Abstract excerpt

BACKGROUND: Although observational studies have suggested a correlation between Sjogren's syndrome (SS) and autoimmune thyroid disease (AITD), a conclusive evidence supporting a causal relationship is still lacking. This study aims to explore the potential causal relationship between SS and AITD. METHODS: Using genome-wide association studies, we performed a bidirectional two-sample Mendelian randomization (MR)...

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• Genome-Wide Association Study
• Graves Disease
• Hashimoto Disease
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide