Article
Causality of Hashimoto's Thyroiditis to Thyroid Cancer: A 2-S Mendelian Randomization Study.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists - 1 Dec 2024
Hu Xiaojie, Wang Yunfei, Liu Erhao, Xiao Wen, Wang Yuying, Liu Yujuan, Que Huafa
Abstract excerpt
BACKGROUND: Observational studies have indicated an association between Hashimoto's thyroiditis (HT) and the risk of thyroid cancer (TC); however, the causality and direction of these effects in genetics remain unclear. Therefore, our study aims to investigate the relationship between genetic susceptibility to HT and TC through a bidirectional Mendelian randomization (MR) approach using twin samples. METHODS: MR...
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