Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Case-Control Study of Factor V Leiden G1691A and MTHFR A1298C Polymorphisms and Clinical Outcomes in Patients With COVID-19.

Immunity, inflammation and disease - 1 Jul 2026

Çıralıoğlu Hilal, Adalı Yasemin, Özen Mert, Oskay Alten, Yılmaz Atakan, Seyit Murat, Köseler Aylin, Türkçüer İbrahim

Abstract excerpt

OBJECTIVE: The clinical relevance of inherited thrombophilia-related polymorphisms in COVID-19 remains uncertain. This study investigated the distribution of Factor V Leiden (FVL) G1691A and MTHFR A1298C polymorphisms in patients with COVID-19 and associations with laboratory findings and short-term mortality. METHODS: This case-control study included 150 patients with PCR-confirmed COVID-19 and 300 controls....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor V

Share to Fibrin Fibrinogen Degradation Products

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Pandemics

Share to SARS-CoV-2

Share to Thrombophilia

Source

Open in PubMed Open full text

Identifiers

PMID: 42504638
DOI: 10.1002/iid3.70493
PMCID: PMC13403049

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Case-Control Study of Factor V Leiden G1691A and MTHFR A1298C Polymorphisms and Clinical Outcomes in Patients With COVID-19.PMID 42504638Read ↗

Thrombophilia genetic mutations and their relation to disease severity among patients with COVID-19.Semantic proximity Read ↗

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortalitySemantic proximity Read ↗

Contribution of genotypes in Prothrombin and Factor V Leiden to COVID-19 and disease severity in patients at high risk for hereditary thrombophilia.Semantic proximity Read ↗

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.Semantic proximity Read ↗

The effect of hereditary thrombotic factors and comorbidities on the severity of COVID-19 disease.Semantic proximity Read ↗

Polygenic predisposition to venous thromboembolism is associated with increased COVID-19 positive testing ratesSemantic proximity Read ↗

Effect of Hereditary Thrombophilia on the Clinical Severity of Covid-19 PneumoniaSemantic proximity Read ↗

Association of polymorphisms in genes encoding prothrombotic and cardiovascular risk factors with disease severity in COVID‐19 patients: A pilot studySemantic proximity Read ↗

Clinical and Genetic Characteristics of Covid-19 Patients from UK BiobankSemantic proximity Read ↗

Venous Thromboembolism in Ambulatory Covid-19 patients: Clinical and Genetic DeterminantsSemantic proximity Read ↗

Missense Variants of von Willebrand Factor in the Background of COVID-19 Associated Coagulopathy.Semantic proximity Read ↗

Prognostic Genetic Markers for Thrombosis in COVID-19 Patients: A Focused Analysis on D-Dimer, Homocysteine and ThromboembolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.