Article
Contribution of genotypes in Prothrombin and Factor V Leiden to COVID-19 and disease severity in patients at high risk for hereditary thrombophilia.
Journal of medical virology - 1 Feb 2023
Kiraz Aslıhan, Sezer Ozlem, Alemdar Adem, Canbek Sezin, Duman Nilgun, Bisgin Atıl, Cora Tulin, Ruhi Hatice Ilgın, Ergoren Mahmut Cerkez, Geçkinli Bilgen Bilge, Sag Sebnem Ozemri, Gözden Hilmi Erdem, Oz Ozlem, Altıntaş Zuhal Mert, Yalcıntepe Sinem, Keskin Adem, Tak Ayşegül Yabacı, Paskal Şeyma Aktaş, Yürekli Uğur Fahri, Demirtas Mercan, Evren Emine Unal, Hanta Abdullah, Başdemirci Müşerref, Suer Kaya, Balta Burhan, Kocak Nadir, Karabulut Halil Gürhan, Cobanogulları Havva, Ateş Esra Arslan, Bozdoğan Sevcan Tuğ, Eker Damla, Ekinci Sadiye, Nergiz Süleyman, Tuncalı Timur, Yagbasan Serap, Alavanda Ceren, Kutlay Nuket Yurur, Evren Hakan, Erdoğan Murat, Altıner Sule, Sanlidag Tamer, Gonen Gizem Akıncı, Vicdan Arzu, Eras Nazan, Eker Hatice Koçak, Balasar Ozgür, Tuncel Gulten, Dundar Munis, Gurkan Hakan, Temel Sehime Gulsun
Abstract excerpt
Thrombotic and microangiopathic effects have been reported in COVID-19 patients. This study examined the contribution of the hereditary thrombophilia factors Prothrombin (FII) and Factor V Leiden (FVL) genotypes to the severity of COVID-19 disease and the development of thrombosis. This study investigated FII and FVL alleles in a cohort of 9508 patients (2606 male and 6902 female) with thrombophilia. It was...
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