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Article

COVID-19 as a Modifier of Genetically Determined Coagulation Phenotype: Implications for Precision Risk Stratification After Infection.

Biochemical genetics - 1 Oct 2026

Perevezentsev Oleg Alexandrovich, Mamedov Ilgar Salekh, Burtsev Dmitry Vladimirovich

Abstract excerpt

Persistent endothelial dysfunction and coagulation abnormalities are increasingly recognized as central components of post-COVID syndrome. However, substantial interindividual variability in long-term coagulation biomarkers suggests the presence of genetically determined susceptibility factors capable of modulating post-infectious thromboinflammatory responses. To determine whether common prothrombotic genetic...

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Topics

Humans
COVID-19
Female
Adult
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Fibrin Fibrinogen Degradation Products

Male

Phenotype

SARS-CoV-2

Factor V

Blood Coagulation

Adolescent

Young Adult

Prothrombin

International Normalized Ratio

Genotype

Genetic Predisposition to Disease

Source

Identifiers

PMID: 42260034
DOI: 10.1007/s10528-026-11414-1

Genes

MTHFR
F2
F5

Variants

Provenance

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