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Article

Thrombophilia genetic mutations and their relation to disease severity among patients with COVID-19.

PloS one - 1 Jan 2024

Moness Hend, Mousa Suzan Omar, Mousa Sarah Omar, Adel Nashwa Mohamed, Ibrahim Reham Ali, Hassan Ebtesam Esmail, Abdelhameed Nadia Ismail, Meshref Dalia Abdelrahman, Abdullah Noha M

Abstract excerpt

OBJECTIVES: Patients with COVID-19 infection appear to develop virus-induced hypercoagulability resulting in numerous thrombotic events. The aim of the present study was to determine the relationship between the thrombophilia genes mutations (prothrombin G20210A, factor V Leiden, and methyltetrahydrofolate reductase (MTHFR)) and the severity of COVID-19 patients. DESIGN: Prospective cross-sectional study. METHOD:...

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Identifiers

PMID: 38507367
DOI: 10.1371/journal.pone.0296668
PMCID: PMC10954113

Genes

MTHFR
CRP

Variants

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