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Article

Missense Variants of von Willebrand Factor in the Background of COVID-19 Associated Coagulopathy.

Genes - 28 Feb 2023

Elek Zsuzsanna, Losoncz Eszter, Maricza Katalin, Fülep Zoltán, Bánlaki Zsófia, Kovács-Nagy Réka, Keszler Gergely, Rónai Zsolt

Abstract excerpt

COVID-19 associated coagulopathy (CAC), characterized by endothelial dysfunction and hypercoagulability, evokes pulmonary immunothrombosis in advanced COVID-19 cases. Elevated von Willebrand factor (vWF) levels and reduced activities of the ADAMTS13 protease are common in CAC. Here, we aimed to determine whether common genetic variants of these proteins might be associated with COVID-19 severity and hemostatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36980889
DOI: 10.3390/genes14030617
PMCID: PMC10048626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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