Parentally imprinted allele typing at a short tandem repeat locus in intron 1a of imprinted gene KCNQ1.

doi:10.1016/j.legalmed.2005.12.002

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Parentally imprinted allele typing at a short tandem repeat locus in intron 1a of imprinted gene KCNQ1.

Legal medicine (Tokyo, Japan) - 1 May 2006

Xu Hong-De, Naito Emiko, Dewa Koji, Fukuda Masaaki, Sumi Hirokazu, Yuasa Isao, Yamanouchi Haruo

Abstract excerpt

A short tandem repeat (STR) in the intron 1a of paternally imprinted gene, KCNQ1, is evaluated as a new probe for use in parentally imprinting allele (PIA) typing. This typing can determine the inheritance of one allele from father by the methylation difference. Allelic and genotypic frequencies of the STR were determined using samples from 175 unrelated Japanese and 170 unrelated Germans. The polymorphism...

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Parentally imprinted allele typing at a short tandem repeat locus in intron 1a of imprinted gene KCNQ1.

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