Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor Profiling Using an NGS Cancer Hotspot Panel in Ukrainian Breast Cancer Patients: Initial Findings of Mutation Frequencies and Clinicopathologic Characteristics.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2026

Gulkovskyi Roman, Fishchuk Liliia, Rossokha Zoia, Gerashchenko Ganna, Bezverkhiy Andrey, Kashuba Volodymyr, Lobanova Olga, Cheshuk Valeriy, Vereshchako Roman, Vershyhora Viktoriia, Popova Olena, Gorovenko Natalia, Tkachuk Zenoviy, Tukalo Mykhailo

Abstract excerpt

BackgroundMolecular profiling with next-generation sequencing (NGS) can improve breast-cancer (BC) diagnostics, prognostication, and treatment selection. Despite this potential, tumor genomic testing has been insufficiently studied and implemented in Ukraine. This exploratory study aimed to identify and clinically analyze variants in tumor suppressor genes, oncogenes, as well as genes involved in epigenetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Cross-Sectional Studies

Share to PIK3CA gene

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Ukraine

Source

Open in PubMed Open full text

Identifiers

PMID: 42495879
DOI: 10.1177/10732748261472065
PMCID: PMC13400919

Genes

PIK3CA
TP53

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor Profiling Using an NGS Cancer Hotspot Panel in Ukrainian Breast Cancer Patients: Initial Findings of Mutation Frequencies and Clinicopathologic Characteristics.PMID 42495879Read ↗

Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing.Semantic proximity Read ↗

The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers.Semantic proximity Read ↗

Identification of Somatic and Germline Mutations Influencing Treatment Outcomes and Disease Susceptibility in Tunisian Triple-Negative Breast Cancer Using Next-Generation Sequencing.Semantic proximity Read ↗

Identification of somatic mutational landscape across Indian breast cancer cases by whole exome sequencing.Semantic proximity Read ↗

Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.Semantic proximity Read ↗

Somatic mutational landscape across Indian breast cancer cases by whole exome sequencing.Semantic proximity Read ↗

Molecular characteristics and prognostic insights into BRCA-associated breast cancer in Kazakhstan.Semantic proximity Read ↗

Deciphering and Targeting Oncogenic Mutations and Pathways in Breast Cancer.Semantic proximity Read ↗

Comparative genomic analysis of PIK3R1-mutated and wild-type breast cancers.Semantic proximity Read ↗

Clinical implications of genomic profiles in metastatic breast cancer with a focus on TP53 and PIK3CA, the most frequently mutated genes.Semantic proximity Read ↗

Detection of activating mutations in liquid biopsy of Egyptian breast cancer patients using targeted next-generation sequencing: a pilot study.Semantic proximity Read ↗

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.