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Article

A genetic signal at 8q12.3 modulates GGT levels via the Runx1-CYP7B1 axis in female ethnic minorities from Guizhou.

Molecular genetics and genomics : MGG - 22 Jul 2026

Yao Qinghai, Chen Ji, Yang Tingting, Lei Changgui, Zeng Shuang, Luo Fei, Hong Feng, Jin Xin

Abstract excerpt

Gamma-glutamyl transferase (GGT) regarded as a biomarker of liver dysfunction or excessive alcohol consumption; however, existing genome-wide association studies (GWAS) have been conducted predominantly in European populations and East Asian populations from Japan and the Taiwan region, with limited investigation in ethnic minorities from Guizhou Province. Previous genetic studies have demonstrated that Guizhou...

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PMID: 42481876
DOI: 10.1007/s00438-026-02484-2

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CYP7B1

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