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Article

Associations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study.

BMC cancer - 10 Jul 2024

Wei Xiaoxia, Yang Chenglei, Lin Qiuling, Qiu Moqin, Wen Qiuping, Zhou Zihan, Jiang Yanji, Chen Peiqin, Liang Xiumei, Cao Ji, Tang Juan, Wei Yuying, Yu Hongping, Liu Yingchun

Abstract excerpt

BACKGROUND: Potentially modifiable risk factors for hepatocellular carcinoma (HCC) have been investigated in observational epidemiology studies in East Asian and European populations, whereas the causal associations of most of these risk factors remain unclear. METHODS: We collected genome-wide association summary statistics of 22 modifiable risk factors in East Asians and 33 risk factors in Europeans. Genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38987736
DOI: 10.1186/s12885-024-12525-x
PMCID: PMC11234530

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