Article
Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping.
Disease models & mechanisms - 1 Dec 2016
Dreger Dayna L, Rimbault Maud, Davis Brian W, Bhatnagar Adrienne, Parker Heidi G, Ostrander Elaine A
Abstract excerpt
In the decade following publication of the draft genome sequence of the domestic dog, extraordinary advances with application to several fields have been credited to the canine genetic system. Taking advantage of closed breeding populations and the subsequent selection for aesthetic and behavioral characteristics, researchers have leveraged the dog as an effective natural model for the study of complex traits,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.