Article
Clearance of NNRTI resistance-associated mutations in the HIV-1 DNA reservoir with or without the presence of M184V mutation.
The Journal of antimicrobial chemotherapy - 2 Jul 2026
Soulie Cathia, Zafilaza Karen, Wirden Marc, Sayon Sophie, Abdi Basma, Cocherie Théophile, Teyssou Elisa, Valantin Marc-Antoine, Faycal Antoine, Schneider Luminita, Pourcher Valérie, Calvez Vincent, Marcelin Anne-Geneviève
Abstract excerpt
BACKGROUND: Recent studies have shown progress in understanding the evolution of HIV antiretroviral resistance-associated mutations (RAMs) in the reservoir, particularly M184V, but data on non-nucleoside reverse transcriptase (RT) inhibitors RAMs (NNRTI-RAMs) remain limited. This study aimed to describe the evolution of NNRTI-RAMs in the reservoir, with or without M184V. MATERIALS AND METHODS: This single-centre...
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