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Article

Kinetics of Archived M184V Mutation in Treatment-Experienced Virally Suppressed HIV-Infected Patients.

The Journal of infectious diseases - 1 Feb 2022

Palich Romain, Teyssou Elisa, Sayon Sophie, Abdi Basma, Soulie Cathia, Cuzin Lise, Tubiana Roland, Valantin Marc-Antoine, Schneider Luminita, Seang Sophie, Wirden Marc, Pourcher Valérie, Katlama Christine, Calvez Vincent, Marcelin Anne-Geneviève

Abstract excerpt

BACKGROUND: We aimed to assess the kinetics of drug-resistant viral variants (DRVs) harboring the M184V mutation in proviral DNA of long-term virally suppressed patients, and factors associated with DRV persistence. METHODS: Human immunodeficiency virus (HIV) DNA from blood cells stored in 2016 and 2019 was sequenced using Sanger and ultradeep sequencing (SS and UDS; detection threshold 1%) in antiretroviral...

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Identifiers

PMID: 34415048
DOI: 10.1093/infdis/jiab413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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