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Article

Treatment Management Challenges in Naïve and Experienced HIV-1-Infected Individuals Carrying the M184V Mutation.

Viruses - 30 Aug 2024

Mimtsoudis Iordanis, Tsachouridou Olga, Akinosoglou Karolina, Metallidis Symeon

Abstract excerpt

M184V is a single-base mutation in the YMDD domain of reverse transcriptase (RT). The M184V resistance-associated mutation (RAM) is related to virological unresponsiveness to lamivudine (3TC) and emtricitabine (FTC) and induces high-level resistance to these two antiretroviral agents. M184V is rapidly selected in the setting of non-suppressive antiretroviral therapy (ART) and accumulates in the HIV reservoir....

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Identifiers

PMID: 39339868
DOI: 10.3390/v16091392
PMCID: PMC11437411

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Treatment Management Challenges in Naïve and Experienced HIV-1-Infected Individuals Carrying the M184V Mutation.PMID 39339868Read ↗

Treatment Management Challenges in Naïve and Experienced HIV-1-Infected Individuals Carrying the M184V MutationSemantic proximity Read ↗

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