Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The RT M184V resistance mutation clearance in the reservoir is mainly related to CD4 nadir and viral load zenith independently of therapeutic regimen type.

The Journal of antimicrobial chemotherapy - 1 Jul 2024

Teyssou Elisa, Soulie Cathia, Fauchois Antoine, Palich Romain, Nouchi Agathe, Sayon Sophie, Abdi Basma, Wirden Marc, Katlama Christine, Pourcher Valérie, Marcelin Anne-Geneviève, Calvez Vincent

Abstract excerpt

OBJECTIVES: Resistance associated mutations (RAMs) are archived in the HIV reservoir and can re-emerge with an inappropriate ART use limiting treatment options. However, recent studies, using ultra-deep sequencing (UDS), showed a decrease of quasispecies harbouring RAMs, suggesting that recycling some antiretrovirals could be considered. The aim of this study was to characterize, in HIV treated PLWHIV, the M184V...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4 Lymphocyte Count

Share to DNA, Viral

Share to Drug Resistance, Viral

Share to HIV Reverse Transcriptase

Share to Proviruses

Share to Viral Load

Source

Identifiers

PMID: 38804140
DOI: 10.1093/jac/dkae164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The RT M184V resistance mutation clearance in the reservoir is mainly related to CD4 nadir and viral load zenith independently of therapeutic regimen type.PMID 38804140Read ↗

Clearance of NNRTI resistance-associated mutations in the HIV-1 DNA reservoir with or without the presence of M184V mutation.Semantic proximity Read ↗

Dynamics of drug resistance-associated mutations in HIV-1 DNA reverse transcriptase sequence during effective ART.Semantic proximity Read ↗

Kinetics of Archived M184V Mutation in Treatment-Experienced Virally Suppressed HIV-Infected Patients.Semantic proximity Read ↗

Treatment Management Challenges in Naïve and Experienced HIV-1-Infected Individuals Carrying the M184V MutationSemantic proximity Read ↗

Treatment Management Challenges in Naïve and Experienced HIV-1-Infected Individuals Carrying the M184V Mutation.Semantic proximity Read ↗

The impact of the M184V resistance mutation on treatment outcomes in patients with HIV infection: a systematic review and meta-analysis.Semantic proximity Read ↗

Deep sequencing analysis of M184V/I mutation at the switch and at the time of virological failure of boosted protease inhibitor plus lamivudine or boosted protease inhibitor maintenance strategy (substudy of the ANRS-MOBIDIP trial).Semantic proximity Read ↗

Transmission dynamics of the M184V drug resistance mutation in primary HIV infection.Semantic proximity Read ↗

HIV DNA Sequencing to Detect Archived Antiretroviral Drug ResistanceSemantic proximity Read ↗

Use of next-generation sequencing on HIV-1 DNA to assess archived resistance in highly treatment-experienced people with multidrug-resistant HIV under virological control: data from the PRESTIGIO Registry.Semantic proximity Read ↗

Detection and quantification of proviral HIV-1 184 M/V in circulating CD4(+) T cells of patients on HAART with a viremia less than 1,000 copies/ml.Semantic proximity Read ↗

HIV-1 DNA ultra-deep sequencing analysis at initiation of the dual therapy dolutegravir + lamivudine in the maintenance DOLULAM pilot study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.