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Article

Germline Multigene Panel Testing in Women With Invasive Lobular Cancer.

JAMA network open - 1 Jul 2026

Corso Giovanni, Marino Elena, Fava Francesca, Natali Fabrizio, Peterlongo Paolo, Dal Molin Matteo, Feroce Irene, Zanzottera Cristina, Massari Giulia, Di Silvestre Susanna, Moscatiello Micol, Franceschini Andrea, Bagnardi Vincenzo, Curigliano Giuseppe, Bonanni Bernardo, Veronesi Paolo, Bertolini Francesco

Abstract excerpt

Importance: Invasive lobular carcinoma (ILC) represents the second most common histologic subtype of breast cancer (BC), yet its genomic landscape and clinical implications remain less well defined compared with invasive ductal carcinoma. Understanding genetic predisposition in ILC may improve risk assessment and guide tailored clinical management. Objectives: To investigate the prevalence and clinical outcomes...

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Topics

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Risk Score

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Source

Open in PubMed Open full text

Identifiers

PMID: 42418202
DOI: 10.1001/jamanetworkopen.2026.21705
PMCID: PMC13347242

Genes

ATM
BARD1
BRCA1
BRCA2
CDH1
CHEK2
FANCM
NF1
PALB2
PTEN
RAD51C
RAD51D
STK11
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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