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Hereditary cancer testing in a diverse sample across three breast imaging centers.

Breast cancer research and treatment - 1 Jan 2024

Westbrook Laura, Miltenburg Darlene, Souter Vivienne, Maisenbacher Melissa K, Howard Katherine L, Sha Youbao, Yavari Maygol, Kypraios Nicholas, Rodriguez Angel, Weitzel Jeffrey N

Abstract excerpt

PURPOSE: Up to 10% of all breast cancers (BC) are attributed to inherited pathogenic variants (PV) in BC susceptibility genes; however, most carriers of PVs remain unidentified. Here, we sought to determine the yield of hereditary cancer gene PVs among diverse women attending breast imaging centers, who could benefit from enhanced surveillance and/or risk reduction interventions. METHODS: This cross-sectional...

Topics

Humans
Female
Aged
Breast Neoplasms
Retrospective Studies
Cross-Sectional Studies
Genetic Testing
Genetic Predisposition to Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37861889
DOI: 10.1007/s10549-023-07137-1
PMCID: PMC10787882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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