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Article

Flow Cytometric Detection of NK Cell KIR Receptors: a Novel Tool for Functional Profiling in Reproductive Failure.

Clinical laboratory - 1 Jul 2026

Kovarova Tereza, Bitoova Martina, Luxova Stepanka, Koudova Monika, Koucky Michal, Cerna Karin

Abstract excerpt

BACKGROUND: Reproductive failures, including recurrent implantation failures (RIF), recurrent pregnancy losses (RPL), and adverse pregnancy outcomes (APO), are increasingly linked to immunological factors at the maternalfetal interface. Killer immunoglobulin-like receptors (KIRs) on natural killer (NK) cells play a key role in regulating maternal immune responses to trophoblast HLA-C antigens. METHODS: In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, KIR

Share to Receptors, KIR2DL1

Source

Identifiers

PMID: 42411671
DOI: 10.7754/Clin.Lab.2025.250730

Genes

C2
KIR2DS1
KIR2DL1
KIR2DL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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