Article
Uterine NK cells underexpress KIR2DL1/S1 and LILRB1 in reproductive failure
13 Jan 2023
Abstract excerpt
A significant proportion of recurrent miscarriage, recurrent implantation failure and infertility are unexplained, and these conditions have been proposed to have an etiology of immunological dysfunction at the maternal-fetal interface. Uterine Natural Killer cells (uNK) comprise three subsets and are the most numerous immune cells found in the uterine mucosa at the time of implantation. They are thought to play...