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Article

Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention.

Reproductive biomedicine online - 1 Dec 2016

Moffett Ashley, Chazara Olympe, Colucci Francesco, Johnson Martin H

Abstract excerpt

A distinctive type of (uterine) natural killer (NK) cell is present in the uterine decidua during the period of placental formation. Uterine NK cells express members of the killer immunoglobulin-like receptor (KIR) family that bind to parental HLA-C molecules on the invading placental trophoblast cells. The maternal KIR genes and their fetal ligands are highly variable, so different KIR/HLA-C genetic combinations...

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Source

Identifiers

PMID: 27751789
DOI: 10.1016/j.rbmo.2016.08.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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