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ERAP, KIR, and HLA-C Profile in Recurrent Implantation Failure

22 Oct 2021

Abstract excerpt

The mother’s uterine immune system is dominated by uterine natural killer (NK) cells during the first trimester of pregnancy. These cells express killer cell immunoglobulin-like receptors (KIRs) of inhibitory or activating function. Invading extravillous trophoblast cells express HLA-C molecules, and both maternal and paternal HLA-C allotypes are presented to KIRs. Endoplasmic reticulum aminopeptidase 1 (ERAP1)...

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Endometriosis Research and Treatment
Pregnancy and Medication Impact
Reproductive System and Pregnancy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34745129
DOI: 10.3389/fimmu.2021.755624

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ERAP, KIR, and HLA-C Profile in Recurrent Implantation FailurePMID 34745129Read ↗

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