Article

Uterine NK cells underexpress receptors recognizing HLA-C2 and HLA-G in reproductive failure

2022-11-25

Abstract excerpt

A significant proportion of recurrent miscarriage, recurrent implantation failure and infertility are unexplained, and these conditions have been proposed to have an etiology of immunological dysfunction at the maternal-fetal interface. Uterine Natural Killer cells (uNK) comprise three subsets and are the most numerous immune cells found in the uterine mucosa at the time of implantation. They are thought to play a...

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Literature Corpus work: 554bc67d-4062-500a-bf03-124cdc3db5c6
DOI: 10.1101/2022.11.25.517971

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