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[Somatic and immune profiling of chemotherapy-associated aplastic anemia: a comparison with primary aplastic anemia and cancer without aplastic anemia].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 May 2026

Zhang Y M, Zhou Y X, Zhuang Q L, Han B

Abstract excerpt

This study aimed to characterize the somatic variant candidate gene profile of patients with chemotherapy-associated aplastic anemia (CAA) and compare it with that of patients with cancer without aplastic anemia (non-AA) and primary aplastic anemia (PAA). This study included 24 patients with CAA diagnosed at Peking Union Medical College Hospital from September 2019 to May 2023 (male-to-female ratio of 3∶5; median...

Topics

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Anemia, Aplastic
Antineoplastic Agents
Exome Sequencing
ATRX gene
DNMT3A gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DRB1 Chains

Source

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Identifiers

PMID: 42409738
DOI: 10.3760/cma.j.cn121090-20251119-00539
PMCID: PMC13416536

Genes

ASXL1
ATRX
BRCA2
DNMT3A
PIK3CA
SAA2
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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