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Article

The Role of Single-Nucleotide Polymorphisms in Acquired Aplastic Anaemia.

Scandinavian journal of immunology - 1 Sept 2026

Luo Yunxiao, Wang Teng, Han Chen, Liu Weilin, Wang Maoyuan, Lyu Chunyi, Xu Ruirong

Abstract excerpt

Acquired aplastic anaemia (AA) is a heterogeneous disease characterized by bone marrow haematopoietic failure, and its pathogenesis is multifactorial, involving immune dysregulation, genetic susceptibility and environmental factors. Single-nucleotide polymorphisms (SNPs) are common single-base genomic variants that are frequent, stable and readily detectable, making them useful markers for studying genetic...

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Topics

Humans
Anemia, Aplastic
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease
Animals
Hematopoietic Stem Cells

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Identifiers

PMID: 42669937
DOI: 10.1111/sji.70149
PMCID: PMC13527175

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