Article
Clinical, surgical, and molecular characteristics and outcomes of adult patients with diffuse midline glioma, H3 K27-altered, treated with surgical resection.
Journal of neuro-oncology - 2 Jul 2026
Lin Jinfeng, Tang Woheng, Li Kaichen, Chen Zhuoyang, Zhang Huayang, Ye Zhi, Li Zhiyong, Qu Shanqiang, Huang Guanglong, Yi Guo-Zhong
Abstract excerpt
PURPOSE: To investigate the clinical, surgical, and molecular features and outcomes of adult patients with diffuse midline glioma (DMG), H3 K27-altered, treated with surgical resection. METHODS: We retrospectively analyzed 52 adult patients with cerebral H3 K27-altered DMG who underwent surgical resection. Next-generation sequencing (NGS) was performed on a subset (n = 20) to characterize the genomic landscape....
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