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H3K27M-Altered Diffuse Midline Gliomas Among Adult Patients: A Systematic Review of Clinical Features and Survival Analysis.

World neurosurgery - 1 Sept 2022

Bin-Alamer Othman, Jimenez Adrian E, Azad Tej D, Bettegowda Chetan, Mukherjee Debraj

Abstract excerpt

OBJECTIVE: The objective of the study was to summarize the clinical characteristics, histo-genomic profiles, management strategies, and survival outcomes of H3K27M-altered adult diffuse midline gliomas (aDMGs). METHODS: PubMed, Scopus, and Cochrane databases were used to identify relevant articles. Papers including H3K27M-altered aDMGs with sufficient clinical outcome data were included. Descriptive clinical...

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Astrocytoma
Brain Neoplasms
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Glioma
Histones

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PMID: 35697228
DOI: 10.1016/j.wneu.2022.06.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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