Article
Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.
Psychological medicine - 1 Sept 2023
Bountress Kaitlin E, Bustamante Daniel, Subbie-Saenz de Viteri Stacey, Chatzinakos Chris, Sheerin Christina, Daskalakis Nikolaos P, Edenberg Howard J, Peterson Roseann E, Webb Bradley T, Meyers Jackie, Amstadter Ananda
Abstract excerpt
BACKGROUND: Posttraumatic Stress Disorder (PTSD) tends to co-occur with greater alcohol consumption as well as alcohol use disorder (AUD). However, it is unknown whether the same etiologic factors that underlie PTSD-alcohol-related problems comorbidity also contribute to PTSD- alcohol consumption. METHODS: We used summary statistics from large-scale genome-wide association studies (GWAS) of European-ancestry (EA)...
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