Article
Effects of repeated culture in sub-inhibitory concentrations of ciprofloxacin on resistance and genetic characteristics of an ocular Pseudomonas aeruginosa isolate.
World journal of microbiology & biotechnology - 29 Jun 2026
Akter Tanzina, Khan Mahjabeen, Stapleton Fiona, Willcox Mark
Abstract excerpt
PURPOSE: To analyse the resistance and genetic changes of a sensitive ocular isolate of Pseudomonas aeruginosa to repeated exposure to subinhibitory concentrations of ciprofloxacin. METHODS: A ciprofloxacin-sensitive ocular isolate P. aeruginosa PA123 was serially passaged under gradually increasing sub-inhibitory concentrations of ciprofloxacin for 18 passages. The minimum inhibitory concentration (MIC) was...
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