Chlorhexidine leads to the evolution of antibiotic-resistant Pseudomonas aeruginosa.

doi:10.1007/s10096-021-04292-5

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Article

Chlorhexidine leads to the evolution of antibiotic-resistant Pseudomonas aeruginosa.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Nov 2021

Tag ElDein Moustafa A, Yassin Aymen S, El-Tayeb Ossama, Kashef Mona T

Abstract excerpt

Antimicrobial resistance is a major public-health concern. We evaluate chlorhexidine role in selection of resistant Pseudomonas aeruginosa mutants and their antibiotic cross-resistance. Mutation frequency and mutation rate after short-term exposure to sub-inhibitory concentrations of chlorhexidine were compared to those after spontaneous chlorhexidine-exposure, in P. aeruginosa PAO1 strain....

Topics

Anti-Bacterial Agents
Bacterial Outer Membrane Proteins
Bacterial Proteins
Ceftazidime
Chlorhexidine
Drug Resistance, Bacterial
Humans
Meropenem
Microbial Sensitivity Tests
Mutation
Pseudomonas Infections
Pseudomonas aeruginosa

Source

Open in PubMed

Identifiers

PMID: 34169445
DOI: 10.1007/s10096-021-04292-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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