Article
Chlorhexidine leads to the evolution of antibiotic-resistant Pseudomonas aeruginosa.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Nov 2021
Tag ElDein Moustafa A, Yassin Aymen S, El-Tayeb Ossama, Kashef Mona T
Abstract excerpt
Antimicrobial resistance is a major public-health concern. We evaluate chlorhexidine role in selection of resistant Pseudomonas aeruginosa mutants and their antibiotic cross-resistance. Mutation frequency and mutation rate after short-term exposure to sub-inhibitory concentrations of chlorhexidine were compared to those after spontaneous chlorhexidine-exposure, in P. aeruginosa PAO1 strain....
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