Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploration of Regulatory Elements, MicroRNAs, and Copy Number Variation in Urogenital Chlamydia Reinfection in African American Women.

International journal of molecular sciences - 16 Jun 2026

Tiwari Hemant K, Vejandla Sandeep Chowdary, Buker Ihsan, Ding Mengchen, Srinivasasainagendra Vinodh, Patki Amit, Gupta Kanupriya, Weinhouse Caren, Geisler William M

Abstract excerpt

Host genetic susceptibility to urogenital Chlamydia trachomatis (Ct) reinfection remains poorly understood. Coding variants identified in prior genome-wide association studies (GWAS) explained only a small fraction of the risk of reinfection. Our goal in this study was to characterize whether more risk would be captured by sequence variation that traditional GWAS insufficiently captures. Specifically, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Chlamydia Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chlamydia trachomatis

Share to DNA Copy Number Variations

Share to Linkage Disequilibrium

Share to MicroRNAs

Share to Regulatory Sequences, Nucleic Acid

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 42353127
DOI: 10.3390/ijms27125410
PMCID: PMC13300433

Genes

CHIT1
ATAD3A
CARD14
DLGAP1
ERICH1
SOCS6
SULF1
TDRP
TMEM240
ZNF140

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploration of Regulatory Elements, MicroRNAs, and Copy Number Variation in Urogenital Chlamydia Reinfection in African American Women.PMID 42353127Read ↗

Genetic susceptibility loci for Chlamydia trachomatis endometrial infection influence expression of genes involved in T cell function, tryptophan metabolism and epithelial integrity.Semantic proximity Read ↗

Mapping Genetic Susceptibility to Urinary Tract Infection from Kidney Papilla to BladderSemantic proximity Read ↗

Conjunctival MicroRNA Expression in Inflammatory Trachomatous ScarringSemantic proximity Read ↗

A common variant rs2272804 in the 5'UTR of RIBC2 inhibits downstream gene expression by creating an upstream open reading frame.Semantic proximity Read ↗

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study.Semantic proximity Read ↗

Chromatin accessibility dynamics of <i>Chlamydia</i> -infected epithelial cellsSemantic proximity Read ↗

Population-based analysis of ocular <i>Chlamydia trachomatis</i> in trachoma-endemic West African communities identifies genomic markers of disease severitySemantic proximity Read ↗

A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections.Semantic proximity Read ↗

A post-GWAS analysis of predicted regulatory variants and tuberculosis susceptibility.Semantic proximity Read ↗

Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan.Semantic proximity Read ↗

A unique insight into the MiRNA profile during genital chlamydial infectionSemantic proximity Read ↗

Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.