Article
Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan.
Mediators of inflammation - 1 Jan 2018
Roberts Chrissy H, Ouburg Sander, Preston Mark D, de Vries Henry J C, Holland Martin J, Morré Servaas A
Abstract excerpt
Chlamydia trachomatis is the most commonly diagnosed bacterial sexually transmitted infection and can lead to tubal factor infertility, a disease characterised by fibrosis of the fallopian tubes. Genetic polymorphisms in molecular pathways involving G protein-coupled receptor signalling, the Akt/PI3K cascade, the mitotic cell cycle, and immune response have been identified in association with the development of...
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