Article
Lactulose-Induced Transcriptional Reprogramming and Repression of Persistence-Associated Phenotypes in Non-Typhoidal Salmonella enterica.
Pathogens (Basel, Switzerland) - 1 Jun 2026
Ahmed Juned, Ajulo Samuel, Shringi Smriti, Haley Bradd J, Shah Devendra H
Abstract excerpt
Lactulose, a synthetic disaccharide widely used in human and veterinary medicine as a therapeutic and prebiotic, is generally assumed to be metabolized exclusively by commensal microbiota. We recently showed that non-typhoidal Salmonella (NTS) can also metabolize lactulose, but the genetic basis and functional consequences remain unclear. Here, we hypothesized that NTS encodes specific genetic determinants and...
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