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Article

Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance.

Antimicrobial agents and chemotherapy - 1 May 2006

Kramer Naomi E, van Hijum Sacha A F T, Knol Jan, Kok Jan, Kuipers Oscar P

Abstract excerpt

Nisin, a posttranslationally modified antimicrobial peptide produced by Lactococcus lactis, is widely used as a food preservative. Yet, the mechanisms leading to the development of nisin resistance in bacteria are poorly understood. We used whole-genome DNA microarrays of L. lactis IL1403 to identify the factors underlying acquired nisin resistance mechanisms. The transcriptomes of L. lactis IL1403 and L. lactis...

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Identifiers

PMID: 16641446
DOI: 10.1128/AAC.50.5.1753-1761.2006
PMCID: PMC1472215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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