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Article

Plasma prothrombin antigenic levels across thrombotic and hemorrhagic phenotypes in triple-positive antiphospholipid patients with antiprothrombin antibodies.

Journal of thrombosis and haemostasis : JTH - 1 Sept 2026

Cattini Maria Grazia, Pontara Elena, Bison Elisa, Tonello Marta, Caforio Alida Linda Patrizia, Pozzi Nicola, Pengo Vittorio

Abstract excerpt

BACKGROUND: The concomitant presence of 4 antiphospholipid antibody types, namely lupus anticoagulant (LA), anticardiolipin antibodies, anti-β2-glycoprotein I, and antiprothrombin antibodies (tetra-positive), constitutes a high-risk antiphospholipid antibody profile and predisposes to thrombosis and catastrophic antiphospholipid syndrome (CAPS). However, tetra-positivity is also seen in asymptomatic carriers with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42297146
DOI: 10.1016/j.jtha.2026.06.010

Genes

CAPS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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