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Article

A Novel ELISA Assay for the Detection of Anti-Prothrombin Antibodies in Antiphospholipid Syndrome Patients at High Risk of Thrombosis.

Frontiers in immunology - 1 Jan 2021

Chinnaraj Mathivanan, Pengo Vittorio, Pozzi Nicola

Abstract excerpt

Autoantibodies targeting prothrombin (aPT) can be found in antiphospholipid syndrome (APS) patients. However, their detection has proven difficult to standardize. Here, we developed a new ELISA assay to improve the identification of aPT and compared its performance with currently available anti-phosphatidylserine/prothrombin antibodies (aPS/PT) and autoantibodies targeting prothrombin bound to the plastic plate...

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Identifiers

PMID: 34567006
DOI: 10.3389/fimmu.2021.741589
PMCID: PMC8455811

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