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Article

Phenotypic Analysis of 26 Cultured TILs Derived From Japanese Melanoma Tissues.

The Journal of dermatology - 1 Aug 2026

Oguma Rena, Koizumi Shigeru, Saeki Yuka, Aoyama Kazuhiro, Kawahara Yu, Matsuzawa Takamitsu, Saito Noriko, Oikawa Ayako, Kawase Katsushige, Honobe-Tabuchi Akiko, Tagashira Ryosuke, Urasaki Chie, Togawa Yaei, Kawamura Tatsuyoshi, Hanazawa Toyoyuki, Kawashima Shusuke, Inozume Takashi

Abstract excerpt

PURPOSE: Tumor-infiltrating lymphocyte (TIL) therapy has attracted increasing attention as a promising next-generation cancer immunotherapy that may overcome some limitations of current immune checkpoint inhibitors. However, the phenotypic characteristics and tumor reactivity of TILs derived from Japanese melanoma tissues remain insufficiently investigated. This study aimed to evaluate the feasibility of...

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Identifiers

PMID: 42271605
DOI: 10.1111/1346-8138.70346
PMCID: PMC13434978

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