Article
Phenotypic analysis of tumor-infiltrating lymphocytes from non-small cell lung cancer and their potential application for adoptive cell therapy.
Immunopharmacology and immunotoxicology - 1 Aug 2020
Ma Yipeng, Ou Jiayu, Lin Tong, Chen Lei, Wang Juntao, Qiao Dongjuan, Lai Shuoyan, Duan Chaojun, Cheng Yuanda, Chang Ruimin, Zhang Chunfang, Wang Mingjun
Abstract excerpt
AIM: Adoptive cell therapy (ACT) of tumor-infiltrating lymphocytes (TILs) has demonstrated clinical benefits in metastatic melanoma treatment. However, the clinical application of TILs produced by a widely used standard protocol from non-small cell lung cancer (NSCLC) can be quite challenging because of the limited clinical benefits. A comprehensive phenotypic knowledge of TILs obtained from NSCLC is important...
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