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Article

APOE-ε4 moderates the association between diet quality and executive function in middle-aged women at increased risk for Alzheimer's disease.

Journal of nutritional science - 1 Jan 2026

Wessinger Chadsley M, Park Kyoung Shin, DuBois Samantha L, Wideman Laurie, Armstrong Brittany D, Vance Jarod C, Kibildis Samuel W, Som-Pimpong Hadassah, Etnier Jennifer L

Abstract excerpt

We examined whether diet quality is associated with executive function (EF) in middle-aged women with a family history of Alzheimer's disease (AD) and whether this is moderated by a genetic AD risk factor, APOE-ε4 allele carriage. Data from 102 low-physically active women (AgeMean = 56.9 ± 5.8 years) were analyzed cross-sectionally. Diet quality was quantified via the Healthy Eating Index-2020 (HEI-2020). Overall...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42267153
DOI: 10.1017/jns.2026.10106
PMCID: PMC13244354

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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