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Article

Polygenic Stroke Risk and Autoimmune Disease: Associations and Clinical Modifiers.

IEEE transactions on bio-medical engineering - 1 Aug 2026

Hornback Andrew, Wang Yifei, Piazzi Marco, Sathu Harinishree, Kim Kyungbeom, Avula Pavithra, Isgut Monica, Wang May D

Abstract excerpt

Polygenic risk scores (PRSs) can improve prediction of complex diseases, but their utility may vary across clinical subgroups with distinct inflammatory or immunologic profiles. Because autoimmune diseases involve chronic immune dysregulation, they may influence both baseline stroke risk and the added value of genetic information in risk prediction. Using the U.K. Biobank, we identified individuals with prevalent...

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Identifiers

PMID: 42262940
DOI: 10.1109/TBME.2026.3702042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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