Article
Comprehensive Genomic Characterization Between Urothelial Carcinoma Subtypes/Divergent Differentiation (S/DD) and Pure Urothelial Carcinoma Using a Large-Scale Japanese Genomic Panel Dataset.
International journal of urology : official journal of the Japanese Urological Association - 1 Jun 2026
Kobayashi Go, Sekino Yohei, Miyamoto Shunsuke, Kobatake Kohei, Kitano Hiroyuki, Goto Keisuke, Goriki Akihiro, Hieda Keisuke, Hayashi Testutaro, Sentani Kazuhiro, Hinata Nobuyuki
Abstract excerpt
OBJECTIVES: Urothelial carcinoma (UC) is a common malignancy; however, UC subtypes/divergent differentiation (S/DD) accounts for only 10%-20% of overall cases. S/DD's aggressive biological behavior significantly affects its prognosis and therapeutic decision-making; thus, elucidating its genomic landscape within UC is important. This retrospective observational study aimed to evaluate and compare the molecular...
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