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Article

Genomic Characterization of Upper Tract Urothelial Carcinoma.

European urology - 1 Dec 2015

Sfakianos John P, Cha Eugene K, Iyer Gopa, Scott Sasinya N, Zabor Emily C, Shah Ronak H, Ren Qinghu, Bagrodia Aditya, Kim Philip H, Hakimi A Ari, Ostrovnaya Irina, Ramirez Ricardo, Hanrahan Aphrothiti J, Desai Neil B, Sun Arony, Pinciroli Patrizia, Rosenberg Jonathan E, Dalbagni Guido, Schultz Nikolaus, Bajorin Dean F, Reuter Victor E, Berger Michael F, Bochner Bernard H, Al-Ahmadie Hikmat A, Solit David B, Coleman Jonathan A

Abstract excerpt

BACKGROUND: Despite a similar histologic appearance, upper tract urothelial carcinoma (UTUC) and urothelial carcinoma of the bladder (UCB) tumors have distinct epidemiologic and clinicopathologic differences. OBJECTIVE: To investigate whether the differences between UTUC and UCB result from intrinsic biological diversity. DESIGN, SETTING, AND PARTICIPANTS: Tumor and germline DNA from patients with UTUC (n=83) and...

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Source

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Identifiers

PMID: 26278805
DOI: 10.1016/j.eururo.2015.07.039
PMCID: PMC4675454

Genes

HRAS
RB1
TP53
ARID1A
CDKN2B
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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